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Synovial tissue transcriptomes of long-standing rheumatoid arthritis are dominated by activated macrophages that reflect microbial stimulation

Advances in microbiome research suggest involvement in chronic inflammatory diseases such as rheumatoid arthritis (RA). Searching for initial trigger(s) in RA, we compared transcriptome profiles of highly inflamed RA synovial tissue (RA-ST) and osteoarthritis (OA)-ST with 182 selected reference tran...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Smiljanovic, Biljana, Grützkau, Andreas, Sörensen, Till, Grün, Joachim R., Vogl, Thomas, Bonin, Marc, Schendel, Pascal, Stuhlmüller, Bruno, Claussnitzer, Anne, Hermann, Sandra, Ohrndorf, Sarah, Aupperle, Karlfried, Backhaus, Marina, Radbruch, Andreas, Burmester, Gerd R., Häupl, Thomas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7220941/
https://ncbi.nlm.nih.gov/pubmed/32404914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64431-4
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