Cell-Specific Type I IFN Signatures in Autoimmunity and Viral Infection: What Makes the Difference?

Gene expression profiling of peripheral blood mononuclear cells (PBMCs) has revealed a crucial role for type I interferon (IFN) in the pathogenesis of systemic lupus erythematosus (SLE). However, it is unclear how particular leucocyte subsets contribute to the overall type I IFN signature of PBMCs a...

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Detalhes bibliográficos
Main Authors: Kyogoku, Chieko, Smiljanovic, Biljana, Grün, Joachim R., Biesen, Robert, Schulte-Wrede, Ursula, Häupl, Thomas, Hiepe, Falk, Alexander, Tobias, Radbruch, Andreas, Grützkau, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877094/
https://ncbi.nlm.nih.gov/pubmed/24391825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083776
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