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Oxyphylla A Promotes Degradation of α-Synuclein for Neuroprotection via Activation of Immunoproteasome

Parkinson’s disease (PD), the second most common neurodegenerative disorder, is neuropathologically characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (SNc) and the presence of Lewy bodies in surviving neurons. α-synuclein (α-syn) is the major component of Lewy b...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Aging Dis
Main Authors: Zhou, Hefeng, Li, Shengnan, Li, Chuwen, Yang, Xuanjun, Li, Haitao, Zhong, Hanbing, Lu, Jia-Hong, Lee, Simon Ming-Yuen
Format: Artigo
Jezik:Inglês
Izdano: JKL International LLC 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7220298/
https://ncbi.nlm.nih.gov/pubmed/32489702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2019.0612
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