Crystal structure of Thermus thermophilus methylenetetrahydrofolate dehydrogenase and determinants of thermostability

The elucidation of mechanisms behind the thermostability of proteins is extremely important both from the theoretical and applied perspective. Here we report the crystal structure of methylenetetrahydrofolate dehydrogenase (MTHFD) from Thermus thermophilus HB8, a thermophilic model organism. Molecul...

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Publicat a:PLoS One
Autors principals: Maiello, Fernando, Gallo, Gloria, Coelho, Camila, Sucharski, Fernanda, Hardy, Leon, Würtele, Martin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7219735/
https://ncbi.nlm.nih.gov/pubmed/32401802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232959
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