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Crystal structure of Thermus thermophilus methylenetetrahydrofolate dehydrogenase and determinants of thermostability

The elucidation of mechanisms behind the thermostability of proteins is extremely important both from the theoretical and applied perspective. Here we report the crystal structure of methylenetetrahydrofolate dehydrogenase (MTHFD) from Thermus thermophilus HB8, a thermophilic model organism. Molecul...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Maiello, Fernando, Gallo, Gloria, Coelho, Camila, Sucharski, Fernanda, Hardy, Leon, Würtele, Martin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7219735/
https://ncbi.nlm.nih.gov/pubmed/32401802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232959
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