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Modeling substrate binding in Thermus thermophilus isopropylmalate dehydrogenase.
The Thermus thermophilus 3-isopropylmalate dehydrogenase (IPMDH) and Escherichia coli isocitrate dehydrogenase (ICDH) are two functionally and evolutionarily related enzymes with distinct substrate specificities. To understand the determinants of substrate specificities of the two proteins, the subs...
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Hlavní autoři: | , |
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Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
Cold Spring Harbor Laboratory Press
1995
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2142962/ https://ncbi.nlm.nih.gov/pubmed/7773180 |
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