Crystallization and preliminary X-ray diffraction analysis of various enzyme–substrate complexes of isopropylmalate dehydrogenase from Thermus thermophilus

The Thermus thermophilus 3-isopropylmalate dehydrogenase (Tt-IPMDH) enzyme catalyses the penultimate step of the leucine-biosynthesis pathway. It converts (2R,3S)-3-isopropylmalate to (2S)-2-isopropyl-3-­oxo­succinate in the presence of divalent Mg(2+) or Mn(2+) and with the help of NAD(+). In order...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Merli, Angelo, Manikandan, Karuppasamy, Gráczer, Éva, Schuldt, Linda, Singh, Rajesh Kumar, Závodszky, Péter, Vas, Mária, Weiss, Manfred S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: International Union of Crystallography 2010
Pynciau:
Crystallization Communications
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882784/
https://ncbi.nlm.nih.gov/pubmed/20516614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430911001626X
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg