Properties and Crystal Structure of Methylenetetrahydrofolate Reductase from Thermus thermophilus HB8

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) is one of the enzymes involved in homocysteine metabolism. Despite considerable genetic and clinical attention, the reaction mechanism and regulation of this enzyme are not fully understood because of difficult production and poor stability. Wh...

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Detalhes bibliográficos
Main Authors: Igari, Sayaka, Ohtaki, Akashi, Yamanaka, Yasuaki, Sato, Yuichi, Yohda, Masafumi, Odaka, Masafumi, Noguchi, Keiichi, Yamada, Kazuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156243/
https://ncbi.nlm.nih.gov/pubmed/21858212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023716
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