Properties and Crystal Structure of Methylenetetrahydrofolate Reductase from Thermus thermophilus HB8

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) is one of the enzymes involved in homocysteine metabolism. Despite considerable genetic and clinical attention, the reaction mechanism and regulation of this enzyme are not fully understood because of difficult production and poor stability. Wh...

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Détails bibliographiques
Auteurs principaux: Igari, Sayaka, Ohtaki, Akashi, Yamanaka, Yasuaki, Sato, Yuichi, Yohda, Masafumi, Odaka, Masafumi, Noguchi, Keiichi, Yamada, Kazuhiro
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156243/
https://ncbi.nlm.nih.gov/pubmed/21858212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023716
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