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Properties and Crystal Structure of Methylenetetrahydrofolate Reductase from Thermus thermophilus HB8

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) is one of the enzymes involved in homocysteine metabolism. Despite considerable genetic and clinical attention, the reaction mechanism and regulation of this enzyme are not fully understood because of difficult production and poor stability. Wh...

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Библиографические подробности
Главные авторы: Igari, Sayaka, Ohtaki, Akashi, Yamanaka, Yasuaki, Sato, Yuichi, Yohda, Masafumi, Odaka, Masafumi, Noguchi, Keiichi, Yamada, Kazuhiro
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156243/
https://ncbi.nlm.nih.gov/pubmed/21858212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023716
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