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Development and validation of LC–MS/MS method for quantification of bictegravir in human plasma and its application to an intracellular uptake study

A sensitive liquid chromatography–tandem mass spectrometry (LC–MS/MS) method was developed and validated for quantification of bictegravir in human plasma. A small volume of only 50 μL aliquot of plasma was precipitated with acetonitrile containing an internal standard (IS). Chromatographic separati...

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Detalles Bibliográficos
Publicado en:Biomed Chromatogr
Autores principales: Prathipati, Pavan Kumar, Mandal, Subhra, Destache, Christopher J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7219634/
https://ncbi.nlm.nih.gov/pubmed/30178512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.4379
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