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LC-MS/MS method for the simultaneous determination of tenofovir, emtricitabine, elvitegravir, and rilpivirine in dried blood spots

A simple, short, and rugged LC-MS/MS method for the simultaneous determination of tenofovir, emtricitabine, elvitegravir and rilpivirine was developed and validated. Dried blood spots were prepared with 25 μL of spiked whole blood. A 3 mm punch was extracted with methanol containing labeled internal...

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Detalhes bibliográficos
Publicado no:Biomed Chromatogr
Main Authors: Prathipati, Pavan Kumar, Mandal, Subhra, Destache, Christopher J
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203670/
https://ncbi.nlm.nih.gov/pubmed/29700852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.4270
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