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Improved nonviral cancer suicide gene therapy using survivin promoter-driven mutant Bax

Suicide gene vectors are being developed in many laboratories as an attractive approach to cancer therapy. However, the development of these therapies is hampered by safety concerns and limitations of efficacy. The use of tumor-specific promoters, such as survivin promoter, can provide much needed s...

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Publicat a:Cancer Gene Ther
Autors principals: Garg, H, Salcedo, R, Trinchieri, G, Blumenthal, R
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7219470/
https://ncbi.nlm.nih.gov/pubmed/19816523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2009.63
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