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Suicide gene therapy for hepatocellular carcinoma cells by survivin promoter-driven expression of the herpes simplex virus thymidine kinase gene

The aim of this study was to investigate the selective killing effect of the herpes simplex virus-thymidine kinase/ganciclovir (TK/GCV) suicide gene system controlled by the survivin promoter on hepatocellular carcinoma (HCC) cells in vitro. Recombinant plasmid vectors driven by the survivin promote...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: QU, LILI, WANG, YANYUN, GONG, LAILING, ZHU, JIN, GONG, RUJUN, SI, JIN
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440221/
https://ncbi.nlm.nih.gov/pubmed/23354806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2013.2248
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