Hemopexin deficiency promotes acute kidney injury in sickle cell disease

Acute kidney injury (AKI) is a major clinical concern in sickle cell disease (SCD). Clinical evidence suggests that red cell alarmins may cause AKI in SCD, however, the sterile inflammatory process involved has hitherto not been defined. We discovered that hemopexin deficiency in SCD is associated w...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Ofori-Acquah, Solomon F., Hazra, Rimi, Orikogbo, Oluwaseun O., Crosby, Danielle, Flage, Bethany, Ackah, Ezekiel B., Lenhart, Diane, Tan, Roderick J., Vitturi, Dario A., Paintsil, Vivian, Owusu-Dabo, Ellis, Ghosh, Samit
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2020
Matèries:
Red Cells, Iron, and Erythropoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218735/
https://ncbi.nlm.nih.gov/pubmed/32043112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019002653
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