Chargement en cours...
Hemopexin therapy reverts heme-induced proinflammatory phenotypic switching of macrophages in a mouse model of sickle cell disease
Hemolytic diseases, such as sickle cell anemia and thalassemia, are characterized by enhanced release of hemoglobin and heme into the circulation, heme-iron loading of reticulo-endothelial system macrophages, and chronic inflammation. Here we show that in addition to activating the vascular endothel...
Enregistré dans:
| Publié dans: | Blood |
|---|---|
| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2016
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4850229/ https://ncbi.nlm.nih.gov/pubmed/26675351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-08-663245 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|