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Histone hyperacetylation mediates enhanced IL‐1β production in LPS/IFN‐γ‐stimulated macrophages

Under the condition of lipopolysaccharide (LPS)/interferon (IFN)‐γ activation, macrophage metabolism is converted from oxidative phosphorylation to glycolysis. In the present work, we analysed whether glycolysis could affect interleukin (IL)‐1β expression through altering histone acetylation levels...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Dong, Zhen, Li, Ruoshui, Xu, Lei, Xin, Kaiyue, Xu, Yamei, Shi, Haiming, Sun, Aijun, Ge, Junbo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218666/
https://ncbi.nlm.nih.gov/pubmed/32061096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13183
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