Neddylation inhibition activates the protective autophagy through NF-κB-catalase-ATF3 Axis in human esophageal cancer cells

BACKGROUND: Protein neddylation plays a tumor-promoting role in esophageal cancer. Our previous study demonstrated that neddylation inhibition induced the accumulation of ATF4 to promote apoptosis in esophageal cancer cells. However, it is completely unknown whether neddylation inhibition could indu...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Liang, Yupei, Jiang, Yanyu, Jin, Xing, Chen, Ping, Heng, Yongqing, Cai, Lili, Zhang, Wenjuan, Li, Lihui, Jia, Lijun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218644/
https://ncbi.nlm.nih.gov/pubmed/32398095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00576-z
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