Neddylation inhibition activates the protective autophagy through NF-κB-catalase-ATF3 Axis in human esophageal cancer cells

BACKGROUND: Protein neddylation plays a tumor-promoting role in esophageal cancer. Our previous study demonstrated that neddylation inhibition induced the accumulation of ATF4 to promote apoptosis in esophageal cancer cells. However, it is completely unknown whether neddylation inhibition could indu...

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Dettagli Bibliografici
Pubblicato in:Cell Commun Signal
Autori principali: Liang, Yupei, Jiang, Yanyu, Jin, Xing, Chen, Ping, Heng, Yongqing, Cai, Lili, Zhang, Wenjuan, Li, Lihui, Jia, Lijun
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218644/
https://ncbi.nlm.nih.gov/pubmed/32398095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00576-z
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