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Antimicrobial and antibiofilm activity of the EeCentrocin 1 derived peptide EC1-17KV via membrane disruption

BACKGROUND: The antibiotic resistance and biofilm formation of pathogenic microbes exacerbate the difficulties of anti-infection therapy in the clinic. The structural modification of antimicrobial peptides (AMP) is an effective strategy to develop novel anti-infective agents. METHOD: Seventeen amino...

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Publicat a:EBioMedicine
Autors principals: Ma, Lingman, Ye, Xinyue, Sun, Pengbo, Xu, Pengfei, Wang, Liping, Liu, Zixiang, Huang, Xiaowei, Bai, Zhaoshi, Zhou, Changlin
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218270/
https://ncbi.nlm.nih.gov/pubmed/32403086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102775
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