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Translational Feasibility of Lumbar Puncture for Intrathecal AAV Administration
Preclinical studies have demonstrated that a single injection of an adeno-associated virus (AAV) vector into the cerebrospinal fluid (CSF) can achieve widespread gene transfer throughout the central nervous system. Successfully translating this approach to humans requires identifying factors that in...
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| Publicat a: | Mol Ther Methods Clin Dev |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Gene & Cell Therapy
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7218226/ https://ncbi.nlm.nih.gov/pubmed/32420410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.04.012 |
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