Inhibiting Airway Smooth Muscle Contraction Using Pitavastatin: A Role for the Mevalonate Pathway in Regulating Cytoskeletal Proteins

Despite maximal use of currently available therapies, a significant number of asthma patients continue to experience severe, and sometimes life-threatening bronchoconstriction. To fill this therapeutic gap, we examined a potential role for the 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR)...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Lu, Robin A., Zeki, Amir A., Ram-Mohan, Sumati, Nguyen, Nhan, Bai, Yan, Chmiel, Kenneth, Pecic, Stevan, Ai, Xingbin, Krishnan, Ramaswamy, Ghosh, Chandra C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218099/
https://ncbi.nlm.nih.gov/pubmed/32435188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00469
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados