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Preserving Airway Smooth Muscle Contraction in Precision-Cut Lung Slices

Precision-cut lung slices (PCLS) are ideal for measuring small airway contraction. However, these measurements are currently limited to acute exposure scenarios that typically last a few minutes to a few hours. Using an insulin-supplemented culture medium, we prolong the small airway contractility i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Li, Guang, Cohen, Jonathan A., Martines, Carolina, Ram-Mohan, Sumati, Brain, Joseph D., Krishnan, Ramaswamy, Ai, Xingbin, Bai, Yan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160136/
https://ncbi.nlm.nih.gov/pubmed/32296115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63225-y
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