Screening for Chemical Toxicity Using Cryopreserved Precision Cut Lung Slices

To assess chemical toxicity, current high throughput screening (HTS) assays rely primarily on in vitro measurements using cultured cells. Responses frequently differ from in vivo results due to the lack of physical and humoral interactions provided by the extracellular matrix, cell-cell interactions...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Watson, Christa Y., Damiani, Flavia, Ram-Mohan, Sumati, Rodrigues, Sylvia, de Moura Queiroz, Priscila, Donaghey, Thomas C., Rosenblum Lichtenstein, Jamie H., Brain, Joseph D., Krishnan, Ramaswamy, Molina, Ramon M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Toxicity Assessment in Cryopreserved Lung Sections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009619/
https://ncbi.nlm.nih.gov/pubmed/26719368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv320
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