Screening for Chemical Toxicity Using Cryopreserved Precision Cut Lung Slices

To assess chemical toxicity, current high throughput screening (HTS) assays rely primarily on in vitro measurements using cultured cells. Responses frequently differ from in vivo results due to the lack of physical and humoral interactions provided by the extracellular matrix, cell-cell interactions...

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Bibliografische gegevens
Gepubliceerd in:Toxicol Sci
Hoofdauteurs: Watson, Christa Y., Damiani, Flavia, Ram-Mohan, Sumati, Rodrigues, Sylvia, de Moura Queiroz, Priscila, Donaghey, Thomas C., Rosenblum Lichtenstein, Jamie H., Brain, Joseph D., Krishnan, Ramaswamy, Molina, Ramon M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
Onderwerpen:
Toxicity Assessment in Cryopreserved Lung Sections
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009619/
https://ncbi.nlm.nih.gov/pubmed/26719368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv320
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