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A High-Throughput System for Cyclic Stretching of Precision-Cut Lung Slices During Acute Cigarette Smoke Extract Exposure

RATIONALE: Precision-cut lung slices (PCLSs) are a valuable tool in studying tissue responses to an acute exposure; however, cyclic stretching may be necessary to recapitulate physiologic, tidal breathing conditions. OBJECTIVES: To develop a multi-well stretcher and characterize the PCLS response fo...

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Publicat a:Front Physiol
Autors principals: Mondoñedo, Jarred R., Bartolák-Suki, Elizabeth, Bou Jawde, Samer, Nelson, Kara, Cao, Kun, Sonnenberg, Adam, Obrochta, Walter Patrick, Imsirovic, Jasmin, Ram-Mohan, Sumati, Krishnan, Ramaswamy, Suki, Béla
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326018/
https://ncbi.nlm.nih.gov/pubmed/32655401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00566
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