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NMR insights into the pre-amyloid ensemble and secretion targeting of the curli subunit CsgA

The biofilms of Enterobacteriaceae are fortified by assembly of curli amyloid fibres on the cell surface. Curli not only provides structural reinforcement, but also facilitates surface adhesion. To prevent toxic intracellular accumulation of amyloid precipitate, secretion of the major curli subunit,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sewell, Lee, Stylianou, Fisentzos, Xu, Yingqi, Taylor, Jonathan, Sefer, Lea, Matthews, Steve
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217966/
https://ncbi.nlm.nih.gov/pubmed/32398666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64135-9
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