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The E. coli CsgB nucleator of curli assembles to β-sheet oligomers that alter the CsgA fibrillization mechanism

Curli are extracellular proteinaceous functional amyloid aggregates produced by Escherichia coli, Salmonella spp., and other enteric bacteria. Curli mediate host cell adhesion and invasion and play a critical role in biofilm formation. Curli filaments consist of CsgA, the major subunit, and CsgB, th...

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Detalhes bibliográficos
Main Authors: Shu, Qin, Crick, Scott L., Pinkner, Jerome S., Ford, Bradley, Hultgren, Scott J., Frieden, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340089/
https://ncbi.nlm.nih.gov/pubmed/22493266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204161109
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