Proteomic analysis reveals a biosignature of decreased synaptic protein in cerebrospinal fluid of major depressive disorder

Major depressive disorder (MDD) is a leading cause of morbidity with a lifetime prevalence of 10%. There is increasing evidence suggesting synaptic dysfunction and impaired integrity of certain brain circuits in MDD. Here we investigate the cerebrospinal fluid proteome of psychiatric patients focusi...

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Publicado no:Transl Psychiatry
Main Authors: Al Shweiki, MHD Rami, Oeckl, Patrick, Steinacker, Petra, Barschke, Peggy, Dorner-Ciossek, Cornelia, Hengerer, Bastian, Schönfeldt-Lecuona, Carlos, Otto, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217933/
https://ncbi.nlm.nih.gov/pubmed/32398672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-0825-7
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