Quantitative Assessment of Elagolix Enzyme-Transporter Interplay and Drug–Drug Interactions Using Physiologically Based Pharmacokinetic Modeling

INTRODUCTION: Elagolix is approved for the management of moderate-to-severe pain associated with endometriosis. The aim of this analysis was to develop a physiologically based pharmacokinetic (PBPK) model that describes the enzyme-transporter interplay involved in the disposition of elagolix and to...

Full description

Saved in:
Bibliographic Details
Published in:Clin Pharmacokinet
Main Authors: Chiney, Manoj S., Ng, Juki, Gibbs, John P., Shebley, Mohamad
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2019
Subjects:
Original Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217817/
https://ncbi.nlm.nih.gov/pubmed/31713224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-019-00833-6
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items