Favorable Pharmacokinetic Characteristics of Extended-Half-Life Recombinant Factor VIII BAY 94-9027 Enable Robust Individual Profiling Using a Population Pharmacokinetic Approach

BACKGROUND: Prophylaxis with factor VIII (FVIII) should be individualized based on patient characteristics, including FVIII pharmacokinetics. Population pharmacokinetic (popPK) modeling simplifies pharmacokinetic studies by obviating the need for multiple samples. OBJECTIVE: The objective of this st...

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Dettagli Bibliografici
Pubblicato in:Clin Pharmacokinet
Autori principali: Solms, Alexander, Iorio, Alfonso, Ahsman, Maurice J., Vis, Peter, Shah, Anita, Berntorp, Erik, Garmann, Dirk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2019
Soggetti:
Original Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217814/
https://ncbi.nlm.nih.gov/pubmed/31749076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-019-00832-7
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