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Direct comparison of two extended half-life PEGylated recombinant FVIII products: a randomized, crossover pharmacokinetic study in patients with severe hemophilia A

An open-label, crossover randomized study was performed to compare the pharmacokinetics (PK) of damoctocog alfa pegol and rurioctocog alfa pegol, two recombinant factor VIII (FVIII) products indicated in patients with hemophilia A, both conjugated to polyethylene glycol to reduce clearance and exten...

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Detalhes bibliográficos
Publicado no:Ann Hematol
Main Authors: Solms, Alexander, Shah, Anita, Berntorp, Erik, Tiede, Andreas, Iorio, Alfonso, Linardi, Camila, Ahsman, Maurice, Mancuso, Maria Elisa, Zhivkov, Tihomir, Lissitchkov, Toshko
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7536163/
https://ncbi.nlm.nih.gov/pubmed/32974838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00277-020-04280-3
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