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Fc-fusion technology and recombinant FVIII and FIX in the management of the hemophilias

Prophylaxis with regular infusions of factor VIII (FVIII)- or factor IX (FIX)- containing products is the mainstay of modern hemophilia care. However, this therapeutic regimen is inconvenient, requiring repeated intravenous injections from childhood. Approaches meant to prolong the half-life of FVII...

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Hlavní autoři: Mancuso, Maria Elisa, Mannucci, Pier Mannuccio
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974692/
https://ncbi.nlm.nih.gov/pubmed/24729686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S47312
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