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Substantial improvement of tetraene macrolide production in Streptomyces diastatochromogenes by cumulative drug resistance mutations

Tetraene macrolides remain one of the most reliable fungicidal agents as resistance of fungal pathogens to these antibiotics is relatively rare. The modes of action and biosynthesis of polyene macrolides had been the focus of research over the past few years. However, few studies have been carried o...

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Publicat a:PLoS One
Autors principals: Fan, Jing-Xuan, Song, Yang, Tang, Gu, Ochi, Kozo, Shentu, Xu-Ping, Yu, Xiao-Ping
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217443/
https://ncbi.nlm.nih.gov/pubmed/32396566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232927
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