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Substantial improvement of tetraene macrolide production in Streptomyces diastatochromogenes by cumulative drug resistance mutations

Tetraene macrolides remain one of the most reliable fungicidal agents as resistance of fungal pathogens to these antibiotics is relatively rare. The modes of action and biosynthesis of polyene macrolides had been the focus of research over the past few years. However, few studies have been carried o...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Fan, Jing-Xuan, Song, Yang, Tang, Gu, Ochi, Kozo, Shentu, Xu-Ping, Yu, Xiao-Ping
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217443/
https://ncbi.nlm.nih.gov/pubmed/32396566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232927
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