Tubular STAT3 Limits Renal Inflammation in Autosomal Dominant Polycystic Kidney Disease

BACKGROUND: The inactivation of the ciliary proteins polycystin 1 or polycystin 2 leads to autosomal dominant polycystic kidney disease (ADPKD). Although signaling by primary cilia and interstitial inflammation both play a critical role in the disease, the reciprocal interactions between immune and...

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Bibliografiset tiedot
Julkaisussa:J Am Soc Nephrol
Päätekijät: Viau, Amandine, Baaziz, Maroua, Aka, Amandine, Mazloum, Manal, Nguyen, Clément, Kuehn, E. Wolfgang, Terzi, Fabiola, Bienaimé, Frank
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Nephrology 2020
Aiheet:
Basic Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217419/
https://ncbi.nlm.nih.gov/pubmed/32238474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019090959
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