Tubule-Specific Mst1/2 Deficiency Induces CKD via YAP and Non-YAP Mechanisms

BACKGROUND: The serine/threonine kinases MST1 and MST2 are core components of the Hippo pathway, which has been found to be critically involved in embryonic kidney development. Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) are the pathway’s main effectors....

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Dades bibliogràfiques
Publicat a:J Am Soc Nephrol
Autors principals: Xu, Chunhua, Wang, Li, Zhang, Yu, Li, Wenling, Li, Jinhong, Wang, Yang, Meng, Chenling, Qin, Jinzhong, Zheng, Zhi-Hua, Lan, Hui-Yao, Mak, Kingston King-Lun, Huang, Yu, Xia, Yin
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2020
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217407/
https://ncbi.nlm.nih.gov/pubmed/32253273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019101052
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