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A Role of the Heme Degradation Pathway in Shaping Prostate Inflammatory Responses and Lipid Metabolism

The molecular mechanisms of prostate inflammation are unclear. We hypothesized that heme oxygenase 1 (HMOX1; HO-1), an enzyme responsible for degradation of heme to carbon monoxide, bilirubin, and iron, is an important regulator of inflammation and epithelial responses in the prostate. Injection of...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Lilljebjörn, Lisa Vikström, Csizmadia, Eva, Hedblom, Andreas, Canesin, Giacomo, Kalbasi, Alireza, Li, Mailin, Kramer, Farah, Bornfeldt, Karin E., Wegiel, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217330/
https://ncbi.nlm.nih.gov/pubmed/32035059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.12.008
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