Translational regulation of periplasmic folding assistants and proteases as a valuable strategy to improve production of translocated recombinant proteins in Escherichia coli

BACKGROUND: Advantages of translocation of recombinant proteins to the periplasm in Escherichia coli include simplified downstream processing, and improved folding and in vivo activity of the target protein. There are, however, problems encountered in the periplasmic production that can be associate...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMC Biotechnol
Egile Nagusiak: Gawin, Agnieszka, Ertesvåg, Helga, Hansen, Sine Alise Hartvigsen, Malmo, Jostein, Brautaset, Trygve
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216727/
https://ncbi.nlm.nih.gov/pubmed/32393331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-020-00615-0
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