Intergroup Randomized Phase III Study of Postoperative Oxaliplatin, 5‐Fluorouracil, and Leucovorin Versus Oxaliplatin, 5‐Fluorouracil, Leucovorin, and Bevacizumab for Patients with Stage II or III Rectal Cancer Receiving Preoperative Chemoradiation: A Trial of the ECOG‐ACRIN Research Group (E5204)

BACKGROUND: The addition of bevacizumab to chemotherapy improved outcomes for patients with metastatic colon cancer. E5204 was designed to test whether the addition of bevacizumab to mFOLFOX6, following neoadjuvant chemoradiation and definitive surgery, could improve overall survival (OS) in patient...

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Pubblicato in:Oncologist
Autori principali: Chakravarthy, A. Bapsi, Zhao, Fengmin, Meropol, Neal J., Flynn, Patrick J., Wagner, Lynne I., Sloan, Jeffrey, Diasio, Robert B., Mitchell, Edith P., Catalano, Paul, Giantonio, Bruce J., Catalano, Robert B., Haller, Daniel G., Awan, Rashid A., Mulcahy, Mary F., O'Brien, Timothy E., Santala, Roger, Cripps, Christine, Weis, John R., Atkins, James N., Leichman, Cynthia G., Petrelli, Nicholas J., Sinicrope, Frank A., Brierley, James D., Tepper, Joel E., O'Dwyer, Peter J., Sigurdson, Elin R., Hamilton, Stanley R., Cella, David, Benson, Al B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2019
Soggetti:
Gastrointestinal Cancer
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216434/
https://ncbi.nlm.nih.gov/pubmed/31852811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2019-0437
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