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Activated CAMKKβ-AMPK signaling promotes autophagy in a spheroid model of ovarian tumour metastasis

BACKGROUND: A hallmark of epithelial ovarian cancer (EOC) metastasis is the process of spheroid formation, whereby tumour cells aggregate into 3D structures while in suspension in the peritoneal cavity. EOC spheroids are subjected to bioenergetic stress, thereby activating AMP-activated protein kina...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Ovarian Res
Päätekijät: Laski, Jeremi, Singha, Bipradeb, Wang, Xu, Valdés, Yudith Ramos, Collins, Olga, Shepherd, Trevor G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216359/
https://ncbi.nlm.nih.gov/pubmed/32393385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-020-00660-5
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