A Novel Role for NUAK1 in Promoting Ovarian Cancer Metastasis through Regulation of Fibronectin Production in Spheroids

Epithelial ovarian cancer (EOC) has a unique mode of metastasis, where cells shed from the primary tumour, form aggregates called spheroids to evade anoikis, spread through the peritoneal cavity, and adhere to secondary sites. We previously showed that the master kinase Liver kinase B1 (LKB1) is req...

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Bibliografische gegevens
Gepubliceerd in:Cancers (Basel)
Hoofdauteurs: Fritz, Jamie Lee, Collins, Olga, Saxena, Parima, Buensuceso, Adrian, Ramos Valdes, Yudith, Francis, Kyle E., Brown, Kevin R., Larsen, Brett, Colwill, Karen, Gingras, Anne-Claude, Rottapel, Robert, Shepherd, Trevor G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280971/
https://ncbi.nlm.nih.gov/pubmed/32429240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12051250
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