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GM1 Oligosaccharide Crosses the Human Blood–Brain Barrier In Vitro by a Paracellular Route

Ganglioside GM1 (GM1) has been reported to functionally recover degenerated nervous system in vitro and in vivo, but the possibility to translate GM1′s potential in clinical settings is counteracted by its low ability to overcome the blood–brain barrier (BBB) due to its amphiphilic nature. Interesti...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Di Biase, Erika, Lunghi, Giulia, Maggioni, Margherita, Fazzari, Maria, Pomè, Diego Yuri, Loberto, Nicoletta, Ciampa, Maria Grazia, Fato, Pamela, Mauri, Laura, Sevin, Emmanuel, Gosselet, Fabien, Sonnino, Sandro, Chiricozzi, Elena
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215935/
https://ncbi.nlm.nih.gov/pubmed/32325905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082858
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