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Parkinson’s disease recovery by GM1 oligosaccharide treatment in the B4galnt1(+/−) mouse model

Given the recent in vitro discovery that the free soluble oligosaccharide of GM1 is the bioactive portion of GM1 for neurotrophic functions, we investigated its therapeutic potential in the B4galnt1(+/−) mice, a model of sporadic Parkinson’s disease. We found that the GM1 oligosaccharide, systemical...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Chiricozzi, Elena, Mauri, Laura, Lunghi, Giulia, Di Biase, Erika, Fazzari, Maria, Maggioni, Margherita, Valsecchi, Manuela, Prioni, Simona, Loberto, Nicoletta, Pomè, Diego Yuri, Ciampa, Maria Grazia, Fato, Pamela, Verlengia, Gianluca, Cattaneo, Stefano, Assini, Robert, Wu, Gusheng, Alselehdar, Samar, Ledeen, Robert W., Sonnino, Sandro
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920361/
https://ncbi.nlm.nih.gov/pubmed/31852959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55885-2
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