Parkinson’s disease recovery by GM1 oligosaccharide treatment in the B4galnt1(+/−) mouse model

Given the recent in vitro discovery that the free soluble oligosaccharide of GM1 is the bioactive portion of GM1 for neurotrophic functions, we investigated its therapeutic potential in the B4galnt1(+/−) mice, a model of sporadic Parkinson’s disease. We found that the GM1 oligosaccharide, systemical...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Chiricozzi, Elena, Mauri, Laura, Lunghi, Giulia, Di Biase, Erika, Fazzari, Maria, Maggioni, Margherita, Valsecchi, Manuela, Prioni, Simona, Loberto, Nicoletta, Pomè, Diego Yuri, Ciampa, Maria Grazia, Fato, Pamela, Verlengia, Gianluca, Cattaneo, Stefano, Assini, Robert, Wu, Gusheng, Alselehdar, Samar, Ledeen, Robert W., Sonnino, Sandro
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920361/
https://ncbi.nlm.nih.gov/pubmed/31852959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55885-2
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky