GM1 Oligosaccharide Crosses the Human Blood–Brain Barrier In Vitro by a Paracellular Route

Ganglioside GM1 (GM1) has been reported to functionally recover degenerated nervous system in vitro and in vivo, but the possibility to translate GM1′s potential in clinical settings is counteracted by its low ability to overcome the blood–brain barrier (BBB) due to its amphiphilic nature. Interesti...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Di Biase, Erika, Lunghi, Giulia, Maggioni, Margherita, Fazzari, Maria, Pomè, Diego Yuri, Loberto, Nicoletta, Ciampa, Maria Grazia, Fato, Pamela, Mauri, Laura, Sevin, Emmanuel, Gosselet, Fabien, Sonnino, Sandro, Chiricozzi, Elena
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215935/
https://ncbi.nlm.nih.gov/pubmed/32325905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082858
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