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Possible Role of Amyloidogenic Evolvability in Dementia with Lewy Bodies: Insights from Transgenic Mice Expressing P123H β-Synuclein

Dementia with Lewy bodies (DLB) is the second most prevalent neurodegenerative dementia after Alzheimer’s disease, and is pathologically characterized by formation of intracellular inclusions called Lewy bodies, the major constituent of which is aggregated α-synuclein (αS). Currently, neither a mech...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Fujita, Masayo, Ho, Gilbert, Takamatsu, Yoshiki, Wada, Ryoko, Ikeda, Kazutaka, Hashimoto, Makoto
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215759/
https://ncbi.nlm.nih.gov/pubmed/32325870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082849
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