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Possible Role of Amyloidogenic Evolvability in Dementia with Lewy Bodies: Insights from Transgenic Mice Expressing P123H β-Synuclein

Dementia with Lewy bodies (DLB) is the second most prevalent neurodegenerative dementia after Alzheimer’s disease, and is pathologically characterized by formation of intracellular inclusions called Lewy bodies, the major constituent of which is aggregated α-synuclein (αS). Currently, neither a mech...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Fujita, Masayo, Ho, Gilbert, Takamatsu, Yoshiki, Wada, Ryoko, Ikeda, Kazutaka, Hashimoto, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215759/
https://ncbi.nlm.nih.gov/pubmed/32325870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082849
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