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Inhibition of Hypoxia-Inducible Factor-1α and Vascular Endothelial Growth Factor by Chrysin in a Rat Model of Choroidal Neovascularization

Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss among the elderly population. Vascular endothelial growth factor (VEGF) is essential for choroidal neovascularization (CNV) development in advanced, wet AMD. Chrysin (5,7-dihydroxyflavone) is a natural flavonoid wi...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Song, Ji Hun, Moon, Ka Young, Lee, Sung Chul, Kim, Sung Soo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215732/
https://ncbi.nlm.nih.gov/pubmed/32325771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082842
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