Winnie-APC(Min/+) Mice: A Spontaneous Model of Colitis-Associated Colorectal Cancer Combining Genetics and Inflammation

(1) Background: Colorectal cancer (CRC) is among the best examples of the relationship between inflammation and increased cancer risk. (2) Methods: To examine the effects of spontaneous low-grade chronic inflammation on the pathogenesis of CRC, we developed a new murine model of colitis-associated c...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: De Santis, Stefania, Verna, Giulio, Serino, Grazia, Armentano, Raffaele, Cavalcanti, Elisabetta, Liso, Marina, Dicarlo, Manuela, Coletta, Sergio, Mastronardi, Mauro, Lippolis, Antonio, Tafaro, Angela, Santino, Angelo, Pinto, Aldo, Campiglia, Pietro, Huang, Alex Y., Cominelli, Fabio, Pizarro, Theresa T., Chieppa, Marcello
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215554/
https://ncbi.nlm.nih.gov/pubmed/32340123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082972
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