Winnie-<i>APC<sup>Min/+</sup></i> Mice: A Spontaneous Model of Colitis-Associated Colorectal Cancer Combining Genetics and Inflammation

(1) Background: Colorectal cancer (CRC) is among the best examples of the relationship between inflammation and increased cancer risk. (2) Methods: To examine the effects of spontaneous low-grade chronic inflammation on the pathogenesis of CRC, we developed a new murine model of colitis-associated c...

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Autors principals: Stefania De Santis, Giulio Verna, Grazia Serino, Raffaele Armentano, Elisabetta Cavalcanti, Marina Liso, Manuela Dicarlo, Sergio Coletta, Mauro Mastronardi, Antonio Lippolis, Angela Tafaro, Angelo Santino, Aldo Pinto, Pietro Campiglia, Alex Y. Huang, Fabio Cominelli, Theresa T. Pizarro, Marcello Chieppa
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2020-04-01
Col·lecció:International Journal of Molecular Sciences
Matèries:
colorectal cancer
murine model
inflammation
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Accés en línia:https://www.mdpi.com/1422-0067/21/8/2972
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