Interleukin 1β Blockade Reduces Intestinal Inflammation in a Murine Model of Tumor Necrosis Factor–Independent Ulcerative ColitisSummary

Background & Aims: Inflammatory bowel diseases are multifactorial diseases commonly treated with either immunomodulatory drugs or anti–tumor necrosis factor (TNF). Currently, failure to respond to anti-TNF therapy (assessed no earlier than 8–12 weeks after starting treatment) occurs in 20%–4...

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Detalhes bibliográficos
Main Authors: Marina Liso, Giulio Verna, Elisabetta Cavalcanti, Stefania De Santis, Raffaele Armentano, Angela Tafaro, Antonio Lippolis, Pietro Campiglia, Antonio Gasbarrini, Mauro Mastronardi, Theresa Torres Pizarro, Fabio Cominelli, Loris Riccardo Lopetuso, Marcello Chieppa
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-01-01
Colecção:Cellular and Molecular Gastroenterology and Hepatology
Assuntos:
Ulcerative Colitis
Cytokines
TNF
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2352345X22000522
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