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Mitochondrial Protection by PARP Inhibition

Inhibitors of the nuclear DNA damage sensor and signalling enzyme poly(ADP-ribose) polymerase (PARP) have recently been introduced in the therapy of cancers deficient in double-strand DNA break repair systems, and ongoing clinical trials aim to extend their use from other forms of cancer non-respons...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Gallyas Jr., Ferenc, Sumegi, Balazs
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215481/
https://ncbi.nlm.nih.gov/pubmed/32316192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082767
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