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Role of Akt Activation in PARP Inhibitor Resistance in Cancer

Poly(ADP-ribose) polymerase (PARP) inhibitors have recently been introduced in the therapy of several types of cancers not responding to conventional treatments. However, de novo and acquired PARP inhibitor resistance is a significant limiting factor in the clinical therapy, and the underlying mecha...

詳細記述

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書誌詳細
出版年:Cancers (Basel)
主要な著者: Gallyas, Ferenc, Sumegi, Balazs, Szabo, Csaba
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7139751/
https://ncbi.nlm.nih.gov/pubmed/32106627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030532
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